The twilek’s opinion on the Republic changes a lot once they realize that the Clones are practicacly slaves.
It starts subtly. When they notice the growing presence of clones are Ryloth isn’t going away, they start to get suspicious. Some twileks get angry but learn to live with it. It isn’t until relationships start to inevitably happen, when the clones admit they are not allowed to get married nor start relationships, do the twileks start to get curious.
“Well maybe when you leave the army!” Some twileks inquire and then they find out leaving the army is also illegal. They find out that having families, and living a life for anything other than the republic is not allowed for the clones. The twileks really start looking into the cloning situation and find out scary things. Clones aren’t allowed to get married, they don’t have freedom. If they leave the army they can be killed.
At a point the kaminoans killed them if they “malfunctioned”. Long story short, the Twileks learn a lot of disturbing things and that turns their animosity toward the Republic. Suddenly, they see the Republic, especially the Jedi as hypocrites. They go around the galaxy freeing slaves only to use slaves and uphold slavery. And that is something that the twileks, so often used as nothing but slaves themselves, can’t let go. Their fears are confirmed when they question the clones directly, and most of them are brutally honest.
So Ryloth is at odds with the Republic, political leaders start proposing for clones to get freedom on Ryloth if they choose, many clones end up missing in action simply because the twileks are covering for them deserting.
This